The typical setup is that I use it horizontally, putting a vertical line at each 45mm mark, leaving me with six sections.
Then I often will split the last two sections horizontally in the middle. Leaving me something similar to 4 standard index cards.
These sections I will typically use for a more “ordered” or focused collection of items. One of them is often capture, another might be work, or if I’m working on planning some project.
The others I use for my hit list. Starting with the first one and just kind of marking things as done or crossing them over as I move, and scribbling over sections as I complete them. Both as a mindful relaxation exercise and as a way to make it easy to see where I have active items.
For some reason I find it so much easier to have consecutive sections of current items instead of have one item, then 10 completed, another one, 8 more completed etc. So I often migrate things ahead.